IBIOME project
Dec 1, 2017
Iberian pig © Manuel Revilla
Title
Genetic and functional validation of QTLs, genes and gene networks and study of microbiome effect on growth, fatness and meat quality in swine
Project coordinator
Host institution
Centre de Recerca en Agrigenòmica (CRAG), Universitat Autònoma de Barcelona (UAB), Bellaterra, Barcelona, Spain
Funding source
Ministry of Economy and Competitiveness (MINECO)
Amount
211 750 €
ID
AGL2014-56369-C2
Publications
Identification of strong candidate genes for backfat and intramuscular fatty acid composition in three crosses based on the Iberian pig
Meat quality has an important genetic component and can be modified by the fatty acid (FA) composition and the amount of fat contained …
Indel detection from Whole Genome Sequencing data and association with lipid metabolism in pigs
The selection in commercial swine breeds for meat-production efficiency has been increasing among the past decades, reducing the …
Association between the pig genome and its gut microbiota composition
The gut microbiota has been evolving with its host along the time creating a symbiotic relationship. In this study, we assess the role …
Characterization of bacterial microbiota compositions along the intestinal tract in pigs and their interactions and functions
In addition to its value in meat production, the pig is an interesting animal model for human digestive tract studies due to its …
Expression analysis of candidate genes for fatty acid composition in adipose tissue and identification of regulatory regions
The aim of this work was to study the genetic basis of the backfat expression of lipid-related genes associated with meat quality …
Association of genetic variants and expression levels of porcine FABP4 and FABP5 genes
The FABP4 and FABP5 genes, coding for fatty acid transport proteins, have long been studied as positional candidate genes for SSC4 QTL …
A global analysis of CNVs in swine using whole genome sequence data and association analysis with fatty acid composition and growth traits
Copy number variations (CNVs) are important genetic variants complementary to SNPs, and can be considered as biomarkers for some …
Integration of liver gene co-expression networks and eGWAs analyses highlighted candidate regulators implicated in lipid metabolism in pigs
In the present study, liver co-expression networks and expression Genome Wide Association Study (eGWAS) were performed to identify DNA …
Analysis of the porcine APOA2 gene expression in liver, polymorphism identification and association with fatty acid composition traits
The APOA2 gene is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig …
Expression-based GWAS identifies variants, gene interactions and key regulators affecting intramuscular fatty acid content and composition in porcine meat
The aim of this work is to better understand the genetic mechanisms determining two complex traits affecting porcine meat quality: …